M ISAPOUR; AR HAKEMI; K EGHBALI; N DAVAR YARI
Volume 15, Issue 1 , March and April 2008, , Pages 20-25
Abstract
Background and Purpose: Clomiphene is the most common drug for the male idiopathic infertility treatment with different results and no valuable factor ha been suggested for prediction of treatment. Therefore the present study was designed to investigate the relationship between early morning total Serum ...
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Background and Purpose: Clomiphene is the most common drug for the male idiopathic infertility treatment with different results and no valuable factor ha been suggested for prediction of treatment. Therefore the present study was designed to investigate the relationship between early morning total Serum Testosterone Level (STL) before treatment and post-clomiphene changes in the spermogram.
Methods and Materials: This clinical trial study was conducted on 172 idiopathic infertile men from 2001 to 2006 in Mashad Iran. Demographic and spermogram data were recorded via questionnaires and patients were divided into 6 groups by their pre-treatment STL. Spermogram parameter changes before and after clomiphene therapy were analysed with SPSS software using t-test ANOVA and Fisher’s test.
Results: Mean age of patients was 31 years; and mean Serum Testosterone Level was 361.3ng/dl. After prescribing clomiphene recovery was observed in the spermogram of in 125 patients (72.7%) with Total Serum Testosterone Level of 200-500ng/dl (P£0.031).
Conclusion: Early morning Serum Testosterone Level can be used as a criterion for predicting the efficacy of clomiphene in male idiopathic infertility.
AR HAKEMI; K EGHBALI; M ISSAPOUR
Volume 12, Issue 4 , January and February 2006, , Pages 28-33
Abstract
Background and Purpose: Urinary stones are the third most common cause of urinary tract disorders and hypercalciuria is reported in 30% to 55% of patients. Therefore, this study is intended to study the serum and urine calcium in patients with urinary stone formation in khorasan, Iran.
Methods and Materials: ...
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Background and Purpose: Urinary stones are the third most common cause of urinary tract disorders and hypercalciuria is reported in 30% to 55% of patients. Therefore, this study is intended to study the serum and urine calcium in patients with urinary stone formation in khorasan, Iran.
Methods and Materials: This descriptive-analytical study was conducted from 2003 summer through 2005 spring on 100 patients (case) and 51 non-patients (control). Relevant data were collected through questionnaire, serum calcium measurement (morning blood sampling) and urinary calcium measurement (24-hour urine collection).
Results: Hypercalciuria was observed in 9% of the case group and 2% of the control group. No significant difference was observed in the urinary calcium of the two groups. (2.23±1.07 vs. 2.13±1.10 mg per kg body weight/24 hours). Hypocalcaemia was detected in one of the cases but in the control group, nobody was so. Also, no significant differences were observed in the serum calcium of the two groups (9.07±0.68 vs. 9.13±0.64 mg/dl).
Conclusion: Compared with references and recent publication, regional hypercaliuria is obviously lower and it is inferred that empirical therapy to prevent stone formation by reducing calcium has no therapeutic role. There seems no need for routine examination of serum calcium.